Fade Age spots,

This loss of insulin sensitivity or, if you wish, the development of insulin resistance, represents loss of receptors for insulin on the surfaces of cells, a process that is influenced by both genes and lifestyle. The Fade Age spots responsible for insulin resistance-”thrifty genes,” as they are sometimes called-are very common in our population because they were selected for by evolution when food was scarce and most people lived near starvation most of the time. If you are frequently on the edge of starvation, loss of sensitivity to insulin is a survival advantage; it allows you to take better advantage of calories when they are available and store them up as fat more efficiently.